Regulation of gene expression by transcription factors, role of receptor tyrosine kinases in cancer malignancies, aberrant gene expression in carcinogenesis, alterations in signal transduction pathways and gene translocations.
Description of Research
The overall goals of the Group are to utilize genomics and proteomics tools and signal transduction resources to accelerate comparative analysis of aberrant gene expression in carcinogenesis and to study alterations in signal transduction pathways during development of cancers.
1. Cell Survival and Apoptosis
2. Transcription factors and cancer
3. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and MDA-7/IL-24
4. The Role of tyrosine kinase receptors in cancer development